Am fi dorit sa citim rezultate ale cercetarii romanesti in domeniu.Avem atata informatie si o scoala romaneasca foarte buna si putem "sa traducem" cu dragoste si cu respect:
A.[« Potential New Alzheimer’s Drugs Advancing in Clinical Trials.
SOURCE : American Chemical Society.
Article Date : 09 Apr 2010 – 0 :00 PDT.
After years of preparation and anticipation ...
Am fi dorit sa citim rezultate ale cercetarii romanesti in domeniu.Avem atata informatie si o scoala romaneasca foarte buna si putem "sa traducem" cu dragoste si cu respect:
A.[« Potential New Alzheimer’s Drugs Advancing in Clinical Trials.
SOURCE : American Chemical Society.
Article Date : 09 Apr 2010 – 0 :00 PDT.
After years of preparation and anticipation , scientists who discover and develop new medications are about to answer a key question about Alzheimer’s disease. Will drugs that block formation of abnormal clumps of protein in the brain called AMYLOID-BETA slow the progression of the devastating disease ?
The cover story in the current issue of Chemical & Engineering News (C&EN), ACS’ weekly newsmagazine , assesses the scientific foundation and clinical landscape of those AMYLOID – BETA BLOCKERS.
C&EN Senior Editor Lisa Jarvis notes that AMYLOID –BETA is at the heart of a central hypothesis and simmering controversy –about Alzheimer’s disease. Some scientists are convinced that AMYLOID –BETA is the root cause of the nerve –cell death and subsequent mental decline in individuals with Alzheimer’s disease. Others think that something else , perhaps a still – unidentified ENVIRONMENTAL NEUROTOXIN is the real culprit . That mystery agent, they suspect, triggers formation of BETA-AMYLOID. If the clinical trials are successful, doctors within 5-10 years could have an arsenal of new drugs that can slow the progression of Alzheimer’s. If the trials fail , its back to the drawing board to find new hypothesis and drug targets for the disease, the article notes.
Article « The Amyloid Question »]SOURCE : Medical News TODAY.
B.« DEMENTIA.
DEMENTIA is not a specific disease. It is a descriptive term for a collection of symptoms that can be caused by a number of disorders that affect the brain. People with dementia have significantly impaired intellectual functioning that interferes with normal activities and relationships. They also lose their ability to solve problems and maintain emotional control , and they may experience personality changes and behavioral problems such as agitation , delusions, and hallucinations. While memory loss is a common symptom of dementia , memory loss by itself does not mean that a person has dementia. Doctors diagnose dementia only it two or more brain functions –such as memory language skills, perception , or cognitive skills including reasoning and judgment –are significantly impaired without loss of conciousness. There are many disorders that can cause dementia. Some, such as AD ( AD = Alzheimer’s disease- after Alois Alzheimer, the German doctor who first described it), lead to a progressive loss of mental functions. But other types of dementia can be halted or reversed with appropriate treatment. With AD and many other types of dementia , disease process cause many nerve cells to stop functioning , lose connections with other neurons, and die. In contrast , normal aging does not result in the loss of large numbers of neurons in the brain.
What Are the Different Kinds of DEMENTIA ?
Dementing disorders can be classified many different ways. These classification schemes attempt to group disorders that have particular features in common , such as whether they are progressive or what parts of the brain are affected. Some frequently used classifications include the following : 1. Cortical dementia ; 2. Subcortical dementia ; 3. Progressive dementia ; 4. Primary dementia ; 5. Secondary dementia. Some types of dementia fit into more than one of these classifictions . For example, AD is considered both a progressive and a cortical dementia.
DEMENTIA in CHILDREN.
While it is usually found in adults , dementia can also occur in children. For example, infections and POISONING can lead to dementia in people of any age. In addition , some disorders unique ti children can cause dementia.
a) Niemann-Pick disease is a group of inherited disorders that affect metabolism and are caused by specific genetic mutations.
b) Batten disease is a fatal, hereditary disorder of the nervous system that begins in childhood.
c) Lafora body disease is a rare genetic disease that causes seizures, rapidly progressive dementia, and movement problems. A number of other childhood –onset disorders can include symptoms of dementia. Among these are mitochondrial myopathies, Rasmussen’s encephalitis, mucopolysaccharidosis III (Sanfilippo syndrome) , neurodegeneration with brain iron accumulation , and leucodystrophies such as Alexander disease , Schilder’s disease, and metachromatic leukodystrophy. » SOURCE : Government.
Cum decembrie a insemnat "implementarea" drogurilor si-n Romania , adica condamnarea la moarte a scolii romanesti de chimie nu este de mirare ca avem si noi cazuri de dementa dorita de unii.
Comentez acest lucru pentru ca in inainte de 1989 se sintetiza TMP, drog la fel de puternic ca si LSD-ul la Centrul de Cercetari Rm.Valcea , afacere a Academiei Romane si avand ca paravan pe acad.dr.ing.Elena Ceausescu. Stim toti ce s-a intamplat dupa aceea.Suntem ofiteri in rezerva si avem grad de sublocotenent in rezerva, arma 52-aparare ciivla, noi profesorii de chimie promotia 1982 interzisi in scolile romanesti din 1982 si pana azi.Cautati in arhivele universitatilor din Cluj, Iasi si Bucuresti, promotia de profesori 1982.
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